and the vast majority of all Food and Drug Administration–approved drugs target proteins. Targeting ncRNAs with drugs ...

Ribo Life's other key drug, RBD1016, targets chronic hepatitis B and hepatitis D. The company has predicted the product will become a cornerstone therapy for hepatitis B in due course. Despite the ...

Immunotherapy uses a person's own immune system to fight cancer. Immune checkpoint inhibitors are one class of immunotherapy ...

Many diseases remain untreatable, not because they are rare or unknown, but because their biological targets are so difficult to drug. Drug discovery, however, is fraught with challenges ...

Researchers at Novartis BioMedical Research in the US and Switzerland have identified a molecular target that may provide a ...

Scientists led by a team at the Medical Research Council (MRC) Mitochondrial Biology Unit, University of Cambridge, have worked out how a molecular machine found in mitochondria—the ...

President Donald Trump on Monday signed a sweeping executive order setting a 30-day deadline for drugmakers to lower the cost of prescription drugs in the U.S. or face new limits over what the ...

Complaints about U.S. drug prices being notoriously high, even when compared with other large and wealthy countries, have long drawn the ire of both parties, but a lasting fix has never cleared ...

Researchers have discovered how to block cells dying, in a finding that could lead to new treatments for neurodegenerative conditions like Parkinson's and Alzheimer's. The team has identified a small ...

However, we believe this novel drug target has potential in the treatment of other neurodegenerative diseases beyond NPC that are still lacking disease-modifying therapies. With this in mind, we are ...