As RNA shapes in individual cells can vary and drive different functions, studying the collective RNA shapes in many cells may overlook the individual variability in both RNA structure and function.

An RNA sequence can therefore be constrained by its coding potential, by its functional structure, and by the need to fold correctly. Understanding the interdependence of these constraints is ...

Atomic AI’s ATOM-1 large language model (LLM) demonstrates state-of-the-art accuracy for predicting RNA structure and function. Technology can be exploited to evaluate and optimize key features ...

With the long-term goal of creating living cells from non-living components, scientists in the field of synthetic biology work with RNA origami. This tool uses the multifunctionality of the natural ...

Cytosine is one of the four main nitrogenous bases found in DNA and RNA, along with adenine (A), guanine (G), and thymine (T) or uracil (U). It is a pyrimidine derivative, meaning it has a single-ring ...

In living organisms today, complex molecules like RNA and DNA are constructed with the help of enzymes. So how did these molecules form before life (and enzymes) existed? Why did some molecules end up ...

To understand how RNA functions, it is essential for scientists to know its 3D structure. Kihara studies protein tertiary structure prediction/comparison, protein-protein docking, protein-ligand ...

The understanding of how RNA structure affects RNA function and the ability to engineer plant genomes at the RNA cellular level, increases the possibility of designing crop types with more ...

Linked to neurological disorders, repeat RNAs aggregate inside droplets but can be disassembled with an engineered piece of ...

Guanine (G) is one of the four main nucleobases found in the nucleic acids DNA and RNA, along with along with adenine (A), cytosine (C), and thymine (T). It is a purine base, meaning it has a ...