Abstracts are available on the EASL Congress 2025 website at https://www.easlcongress.eu/. The posters are expected to be made available to conference attendees at the start of the meeting on May 7, ...

Dose-responsive increases in PD-L1 receptor occupancy were observed in peripheral blood cells, which correlated with dose-dependent increases in AB-101 plasma concentrations. The clinical plasma ...

Patients with CLL and a CSHA CFS score greater than 3 had significantly higher rates of treatment interruption due to adverse effects.

Data we have so far from RAP-219 shows a degree of brain receptor occupancy of RAP-219 that, in preclinical models, has been associated with therapeutic levels of protection from seizures.

NTX-1955 has completed a comprehensive non-clinical package as well as Phase 1 trials, including single and multiple ascending dose studies, drug-drug interaction, and receptor occupancy studies, ...

Rather than focusing solely on detecting adverse side effects, biomarkers can be monitored in patients to determine the optimal dose based on specific physiological responses, such as receptor ...

receptor occupancy relationships of LPA1 antagonists in the human lung. This study describes the radiosynthesis of [18F]-BMT-083133, a LPA1 antagonist, as a potential PET radioligand. Methods Several ...