Apart from carrying the information to encode proteins in, RNA molecules can adopt intricate 2D and 3D structures. Specifically, the same RNA molecule can switch between ON and OFF structures, ...

eLife Assessment This important study offers convincing evidence that intra-Golgi transport slows from cis to trans and varies between cargos even within the same cisternae, supporting a more stable ...

With a new mapping tool, Princeton engineers have revealed how a factory inside cells builds ribosomes, the machinery responsible for protein synthesis.

The ability of a ribosome to decode mRNA without shifting between reading frames is a strict requirement for accurate protein biosynthesis. Despite enormous progress in understanding the mechanism of ...