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Introduction: During T cell development, heterogeneous nuclear ribonucleoprotein (hnRNP) L is known to regulate CD4 T helper subset differentiation ... the spleens were isolated and assessed via flow ...

Mechanism whereby T cell plasticity, a process originating in the gut and aided by gut microbiota, promotes autoimmunity at gut-distal sites.

Specific host factors, such as immune cell activity, sex hormones and microbiota composition, influence the ability of Staphylococcus aureus bacteria to colonize the gut of mice.

A team of researchers from the Keck School of Medicine of USC has developed an advanced tool for analyzing chimeric antigen ...

The team tested the impact on eight novel helper plasmids with different deletions in the E2 and E4 genes on four rAAV serotypes. They discovered that some deletions affected productivity, reducing ...

In this case, reprogrammed T helper cells adopt characteristics of a new T helper cell type while preserving some of their original traits, making them "super powerful and potent – and if you ...

Cytotoxic T cells are star players in the adaptive immune system, enforcing protection against invading viruses or cancer cells. However, evidence has been mounting that the cells may also deal a ...

The scientists showed that, right at the onset of mild illness, the body also produces special T cells previously known only from chronic, severe infections and tumors. There are different types ...