T-bet is a transcription factor, one of the control proteins in the cell nucleus that can turn specific groups of genes on ...

This review focuses on the unique characteristics of mitochondrial nucleoids in mammalian cells, highlighting their ...

Using detailed genetic analysis and manipulation, researchers show that continuous T-bet expression in these cells is key to ...

At the surface, the immune response to a flu virus is simple. Some cells recognize the pathogen and send a signal to the ...

Scientists at Johns Hopkins have discovered how a natural RNA molecule can block HIV from reactivating, opening doors to a ...

Specific way genetic material is organized in cells determines its ability to adapt to resist treatment. Scientists modulated ...

Scientists create smart cells that administer automatic treatments from inside the human body, reacting within seconds to ...

Macrophages are immune cells with a split personality: some fight tumors, while others help them grow. In breast cancer, most macrophages fall into the latter camp—dubbed M2-like—fueling tumor ...

For decades, the dream of fixing harmful mutations in mitochondrial DNA felt out of reach. Scientists have long known these ...

Stressed DNA sets off a cascade of failures in the body linked to heart conditions, neurodegeneration, and chronic inflammation. A new, UCR-designed tool interrupts this process, preserving DNA before ...

Immune checkpoints are regulatory proteins that prevent the immune system from attacking healthy tissues. Some cancer cells ...