Melbourne scientists are teasing out how the "Hippo pathway" works at the molecular level, improving understanding of how it ...

With this in mind, Zidovska and her colleagues focused on RNA polymerase II—responsible for the transcription and one of the most abundant molecular motors in the cell nucleus.

Understanding the mechanics behind transcription-dependent motions of single genes in the nucleus might be critical for understanding the human genome in health and disease." ...

Scientists create smart cells that administer automatic treatments from inside the human body, reacting within seconds to ...

T-bet is a transcription factor, one of the control proteins in the cell nucleus that can turn specific groups of genes on ...

In addition to exporting materials out of the nucleus, the protein, called Exportin-1 (also called Xpo1 or Crm1), seems to play a role in promoting gene transcription, the process that creates RNA ...

Using detailed genetic analysis and manipulation, researchers show that continuous T-bet expression in these cells is key to ...

In addition to exporting materials out of the nucleus, the protein, called Exportin-1 (also called Xpo1 or Crm1), seems to play a role in promoting gene transcription, the process that creates RNA ...

The researchers believe this could be a potentially useful tool for delivering drugs to the nucleus more quickly, or by tagging transcription factors to increase the activity of certain genes.

At the surface, the immune response to a flu virus is simple. Some cells recognize the pathogen and send a signal to the ...