Its dual configuration binds the CD8 Treg receptors, KIR and CD8, to selectively activate CD8 Treg and enhance MTX-101's specificity, respectively.

These regulations manage the use and occupancy of the public lands under the United States mining laws by limiting such use or occupancy to prospecting, mining, or processing operations and uses ...

The histamine subtype 3 receptor (H3R) is a G protein-coupled receptor involved in various central nervous system (CNS) disorders. We herein describe the identification and preclinical evaluation of ...

GLP-1 receptor agonists and amylin receptor agonists have shown clinically relevant weight loss and glucose-lowering effects in people with overweight, obesity, and type 2 diabetes. Amycretin is a ...

El Paso County Commissioner David Stout is considering the use of hotel occupancy taxes to fund significant projects, and this can include the proposed Downtown ...

Improving the balance between proinflammatory T cells and anti-inflammatory regulatory T cells (Tregs) may be an attractive approach for treating atherosclerosis. Although C-C chemokine receptor 4 ...

It competitively antagonizes all opioid-receptor sites, including the μ, κ, and δ sites. Naloxone has no opioid effects.