According to DelveInsight’s analysis, the growth of the urea cycle disorders market is expected to be mainly driven by increasing prevalence, patient awareness, advancements in newborn screening ...

More information: Yiming Zhang et al, Hierarchical tricarboxylic acid cycle regulation by hepatocyte arginase 2 links the urea cycle to oxidative metabolism, Cell Metabolism (2024). DOI: 10.1016/j ...

By identifying the critical role the urea cycle plays in its development, his findings could pave the way for new medications to treat this currently incurable disease.

Their latest findings further suggest that targeting nitrogen handling in the liver, a process linked to the urea cycle, could be an effective treatment approach. Related Stories.

Researchers at the Center for Cognition and Sociality reveal the presence of a functional urea cycle in the star-shaped cells of the Alzheimer’s Disease (AD) brain. Key results point to the role ...

Boehringer Ingelheim will be commencing a new collaboration with Thoeris GmbH with the goal of advancing a first-in-class approach for the treatment of urea cycle disorders (UCDs) independent of ...

Astrocytic urea cycle detoxifies Aβ-derived ammonia while impairing memory in Alzheimer’s disease. Cell Metabolism , 2022; DOI: 10.1016/j.cmet.2022.05.011 Cite This Page : ...

Hierarchical tricarboxylic acid cycle regulation by hepatocyte arginase 2 links the urea cycle to oxidative metabolism. Cell Metabolism , 2024; DOI: 10.1016/j.cmet.2024.07.007 Cite This Page : ...