Most species of bacteria can be broadly divided into two groups, known as gram-positive and gram-negative. These categories reflect big differences in the microbes' biology, and they also dictate how ...

Gram-positive and gram-negative bacteria differ in the composition of their cell walls. Gram-negative bacteria have a double layer of protection, making them more difficult to kill, Muñoz said.

The duration of antibiotic therapy for GN-BSIs varied across US hospitals and was commonly longer than 10 days, including in patients with uncomplicated bacteremia.

Seven days of antibiotics was noninferior to 14 days for treating Gram-negative bloodstream infections, supporting shorter ...

Gram-negative meningitis is a form of meningitis. The term gram-negative refers to a way of differentiating bacteria. This type of bacteria is typically resistant to drugs and most available ...

Home Topics Drug Discovery Synthetic Antibiotic Strategy against Gram-Negative Bacteria August 10, 2023 Credit: libre de droit / 1338313586 / iStock / Getty Images Plus ...

Gram-negative bacteria comprise most of the CDC and WHO’s lists of critical and urgent antibiotic-resistant organism threats. The problem of gram-negative resistance was exacerbated by the COVID ...

The new drug’s target is an enzyme called LpxC that is the second enzyme in the “Raetz pathway” and is essential to making the outer membrane lipid in gram-negative bacteria. Raetz joined Duke as the ...

Source Reference: Tingsgard S, et al "Early switch from intravenous to oral antibiotics for patients with uncomplicated gram-negative bacteremia" JAMA Netw Open 2024; DOI: 10.1001/jamanetworkopen ...

In collaboration with the Robert Koch Institute (RKI), the National Reference Centre (NRC) for multidrug-resistant Gram-negative bacteria, based at Ruhr University Bochum, has proved that many of ...