A global team mapped over 100,000 structural variants in human genomes by applying Oxford Nanopore long-read sequencing and a ...

In a first-of-its-kind experiment tracing evolution across 25 generations, scientists have discovered that marine ...

The fungus behind yeast infections is a mercurial beast, and there's something specific in human blood that may flip its ...

A research team led by the Leibniz-HKI in Jena has uncovered a new way in which the yeast Candida albicans can damage human ...

Lac insects carry a yeast-like symbiont that produces a commercially important bright red pigment, revealing insights about ...

Single-cell T cell sequencing and T cell receptor (TCR) sequencing showed i) a decrease in TCR diversity in CML; ii) an expansion of CD8 TE cells in CML; iii) enrichment of a large number of CD8 ...

But nearly all of those experiments have taken place in simple organisms like bacteria or yeast. These systems are fast and easy to manipulate, but they lack the complexity of human cells ... with ...

Methods: We analyzed 74 single-cell RNA sequencing (scRNA-seq) samples, performing unsupervised clustering and marker-gene expression profiling to define major cell types. Large-scale chromosomal copy ...

This is a useful study in the role of CHI3L1 in Kupffer cells, the macrophages of the liver, showing that CHI3L1 alters glucose regulation in obesity. Specifically, Chi3l1 protects glucose-dependent ...

To overcome these limitations, the researchers engineered common brewer's yeast cells to individually produce different macrocyclic peptides.