Modular synthesis of polycyclic ring expansion substrates. The requisite polycyclic enol ether and enamine substrates for ring expansion were synthesized as shown in Figure 2.Cyclic ketones 6 were ...

Rice University scientists have given organic chemists a boost with their latest discovery of a one-step method to add nitrogen to compounds for drugs, pesticides, fertilizers and other products ...

Herein, we report a formal synthesis of (±)-englerin A (1) via regio- and diastereoselective [4+3] cycloaddition between the 2,5-disubstituted furan and formyl enol silyl ethers, which possesses ...

Poly(β-keto enol ether) Prepared by Three-Component Polycondensation of Bis(diazoketone), Bis(1,3-diketone), and Tetrahydrofuran: Mild Acid-Degradable Polymers To Afford Well-Defined Low ...

The resulting polymer, poly(β-keto enol ether), was highly sensitive to mild acidic conditions and degraded into a combination of well-defined low molecular weight compounds.

This course aims to provide deepened and widened knowledge of concepts, reactivity, and synthesis in organic chemistry. It encompasses: carbonyl/enol/enolate chemistry, frontier molecular orbital ...

Being able to synthesize azulenes from readily available 2H-cyclohepta[b]furan-2-one derivatives and silyl enol ether is a great step forward in practical applications.