In any study, observations on each individual are made. These observations vary both between and within individuals and are thus referred to as “variables.” We may summarise the data collected in a ...

Publishes original research, insights and opinions on evidence-based research. Focuses on the tools, methods, and concepts that are central to practising evidence-based medicine.

Focusing on a specific example from community care, this article argues that clinical guidelines will be better and more usable if they incorporate the findings of high-quality, qualitative research.

Published research should be reported to evidence users with clarity and transparency that facilitate optimal appraisal and use of evidence and allow replication by other researchers. Guidelines for ...

There is a recognised knowledge deficit about the absolute size of benefits and harms of treatments among clinicians1 2 restricting the possibility of good quality shared decision-making3 4 and ...

Objectives To compare the effectiveness of different exercise interventions in improving sleep quality and alleviating insomnia severity among patients with insomnia. Design Our study design was a ...

Health literacy demands placed on patients and consumers are amplified in low-value care contexts and must be addressed as a system and organisational priority, argue Danielle Muscat and colleagues . ...

Case reports and case series are uncontrolled study designs known for increased risk of bias but have profoundly influenced the medical literature and continue to advance our knowledge. In this guide, ...

Existing reporting checklists lack the specificity and comprehensiveness required to effectively guide the documentation of acupuncture case reports. Therefore, we developed a reporting guideline ...

Healthcare delivery is being transformed by the rapid growth of data, advancements in artificial intelligence (AI) and other technologies. In healthcare, obtaining real-world data can be ...

Objective This study evaluates whether Taiwan’s national oral cancer screening programme, implemented in 1999, has led to a reduction in late-stage oral cancer and mortality. Design An observational ...