7 In leptomeningeal hATTR, the CNS is affected due to the deposition of amyloid in the pial and arachnoid membranes and in the walls of vessels in the subarachnoid space. 6,7 Patients carrying an ...

Medications like lecanemab (Leqembi) and donanemab (Kisunla) target amyloid plaques in the brain that build up due to Alzheimer’s disease. They may help slow disease progression for people in ...

The Medicines and Healthcare products Regulatory Agency (MHRA) has approved the medicine acoramidis (Beyonttra) to treat adult patients with cardiomyopathy (damage to the heart muscle) caused by ...

Vutrisiran is currently approved in the European Union (EU) under the brand name AMVUTTRA ® for the treatment of hereditary transthyretin-mediated (hATTR) amyloidosis in adult patients with stage ...

Division of Pharmacology, Faculty of Medicine, Tohoku Medical and Pharmaceutical University, Sendai 983-8536, Japan Department of Pharmacology, Tohoku University Graduate School of Medicine, Sendai ...

Vutrisiran is currently approved in the European Union (EU) under the brand name AMVUTTRA ® for the treatment of hereditary transthyretin-mediated (hATTR) amyloidosis in adult patients with stage 1 or ...

The following is a summary of “Elevated serum concentrations of GFAP in hereditary transthyretin amyloidosis since pre-symptomatic stages,” published in the April 2025 issue of Journal of Neurology by ...

A team of scientists including UCL researchers has tested four anti-amyloid Alzheimer's therapeutics to find out how the drugs bind to toxic amyloid beta protein to tackle the disease. Using new ...

Pollen is a common allergen that can aggravate eyes. Pinguecula and pterygium are growths that appear on your eye’s conjunctiva, the clear covering that sits on the white part of the eye.

There are three major subtypes of amyloidosis: primary amyloidosis, secondary amyloidosis, and hereditary amyloidosis (Khan & Falk, 2001; Nakata & Shimamoto, 2003; Smith, 2003). Primary ...