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The ongoing challenge posed by viral infections to global health has been exemplified by the SARS-CoV-2 pandemic and the continuous threats from pathogens ...
Targeting clonal antigens and circumventing dysfunctional states may be important for conferring clinical responses to TIL therapy.
After issues at a third-party manufacturer caused the FDA to reject Regeneron's multiple myeloma bispecific antibody ...
Irritable bowel syndrome, chronic itching, asthma and migraine are in many cases hard-to-treat conditions. They have in common that they are triggered by an excessive immune response -- which in ...
ANTIGEN–ANTIBODY complexes can dissociate under suitable conditions (increased ionic strength, extreme pH values), which indicates that the reaction depends on the medium and is reversible.
Exposing children with peanut allergy to proteins from the legume is an approved treatment to reduce the risk of allergic ...
Each antibody produced by your immune system binds to a specific antigen and then either destroys the pathogen or tags it so other immune cells will recognize it. Antibodies are also known as ...
The use of glutaraldehyde to circumvent these difficulties was considered because this fixative has two reactive aldehyde groups which might attach simultaneously to antibody and antigen and bind ...
In experiments in mice, the team found that when new foods were introduced to the guts of the animals soon after damage to the skin, the mice developed allergic reactions to them. The injuries boosted ...
Once they had identified a lead candidate antibody, which they named NEO-201, the next step was to identify its target antigen ... targets triggered an immune reaction in patients.
Laboratory of Macromolecular and Organic Chemistry, Institute for Complex Molecular Systems, Eindhoven University of Technology, P.O. Box 513, Eindhoven 5600 MB, The Netherlands ...