The lung is one of the most fascinating and intricate immunological sites of the human body. The lower respiratory tract is covered with a 75 m 2 monolayer of epithelial cells that separate the ...

A CD4/CD8 cut-off value below 0.4 showed the strongest association ... San Jose, CA). The following antibodies were used in this study: fluorescein isothiocyanate (FITC)-conjugated-CD57; phycoerythrin ...

PE-Cy7-conjugated anti-mouse CD4 (RM4-5), PE- and APC-conjugated anti-mouse CD8a ... Functional grade monoclonal antibodies for murine CD3 (145-2C11) and CD28 (37.51) and neutralizing anti-IL4 (11B11) ...

To reach this goal, we need to go beyond designing molecules that simply bind to a target. Instead, we must develop antibodies that are capable of sampling the cell surface to distinguish between ...

The test doesn't detect the virus itself but instead detects antibodies—called immunoglobulin G (IgG)—produced by the immune system in response to the virus. A positive test result indicates that you ...

The US Food and Drug Administration announced Thursday that it will be phasing out a requirement that monoclonal antibodies and other drugs be tested on animals, saying in a news release that ...

The FDA said it plans to phase out animal testing requirements for monoclonal antibodies and other drugs, replacing them with “more effective, human-relevant methods.” Shares in Charles River ...

Credit: Dalin Ou via Getty Images. US biotech Merida Biosciences has launched with $121m in Series A financing to develop therapeutics targeting disease-causing antibodies in autoimmune diseases and ...

Global pharmaceutical stocks plunged on the news Wednesday, with U.K.-based AstraZeneca dropping 5% and Swiss drugmaker Novartis losing 3% in early trading on U.S. exchanges. Top U.S. drugmakers, ...