Lipid nanoparticles (LNPs) and liposomes (Figure 1) have revolutionized the medical field by serving as carriers for a wide range of therapeutic molecules, | Drug Discovery And Development ...

Immune cell-derived extracellular vesicles (EVs) possess intrinsic immunomodulatory properties, making them potential vaccine adjuvants. Here, we show that EVs from mature bone marrow-derived ...

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Different purification methods—such as ultracentrifugation or size-exclusion chromatography—can impact exosome yield and quality.

A research team at the University of Osaka has unveiled the molecular mechanism behind genome ejection from adeno-associated virus (AAV) vectors, a crucial delivery vehicle in gene therapy.

To explore the role of lysine myristoylation in this process, we performed subcellular fractionation and generated low- and high-density membrane fractions via ultracentrifugation.

DGIST scientists created the first practical next-gen betavoltaic cell using carbon-14 and perovskite. Scientists have achieved a major breakthrough by creating the world’s first next-generation ...

The Golgi colocalization of Oxr1 and Ncoa7 was further confirmed by subcellular fractionation using density gradient ultracentrifugation.

Using Design of Experiment (DoE) optimization, the upstream process achieved a yield exceeding 3e15 vg/L at 50L scale, supported by a streamlined downstream process including single-use clarification, ...