New research uncovers an immune pathway driving acute chest syndrome in sickle cell disease; blocking it with approved drugs ...

Sickle cell disease can lead to a severe complication known as acute chest syndrome (ACS), but the underlying mechanisms are ...

Sickle cell disease can lead to a severe complication known as acute chest syndrome (ACS), but the underlying mechanisms are not well understood. A new study by Mass General Brigham investigators ...

Pain isn't just a physical sensation—it also carries emotional weight. That distress, anguish, and anxiety can turn a fleeting injury into long-term suffering.

Breaking out in a cold sweat without physical exertion or heat is a warning sign that many people overlook. During a heart attack, the body releases stress hormones like adrenaline, which can cause ...

Discover 10 common causes of chest discomfort specific to women. Learn when chest pain signals serious conditions versus benign causes requiring care.

Patients with chest pain who have a sedentary lifestyle are at higher risk for more heart problems and death within the year following hospitalization.

Scientists have recreated a pathway that senses pain, using clusters of human nerve cells grown in a dish.

Stanford Medicine investigators have replicated, in a lab dish, one of the most prominent human nervous pathways for sensing pain. This nerve circuit transmits sensations from the body’s skin to ...