An international team led by Einstein Professor Cecilia Clementi in the Department of Physics at Freie Universität Berlin has ...

A new study led by Freie Universität Berlin physicist and recently published in Nature Chemistry opens up, among other things ...

Diffusion models have demonstrated exceptional ability in modeling complex image distributions, making them versatile plug-and-play priors for solving imaging inverse problems. However, their reliance ...

In this letter, denoising diffusion implicit models (DDIM), a computation-efficient class of probabilistic diffusion models, are proposed for improving the reconstruction performance of end-users in ...

In particular, we engineer the transition from two-state to downhill folding by tuning the cooperativity of a protein model that folds in a two-state fashion at the midpoint and reaches downhill ...

Tool aims to solve the mystery of non-coding sequences — but is still in its infancy.

Proteins that fold over free-energy barriers ≤ 3RT are classified as downhill folders. This regime is characterized by equilibrium unfolding that is proportionally broader and more complex the lower ...

Proteins mediate their functions through chemical interactions; modeling these interactions, which are typically through sidechains, is an important need in protein design. However, constructing an ...

In this work, the researchers showed how water molecules near a protein surface can influence misfolding. A mutation that is related to tauopathies has a subtle effect on water's dynamic structure in ...