Q1 2025 Earnings Call Transcript May 1, 2025 Alkermes plc misses on earnings expectations. Reported EPS is $0.13 EPS, expectations were $0.28. Operator: Greetings, and welcome to Alkermes’ First ...

No vomiting was seen in this dose group. - Data from three different ... small molecule GLP-1 receptor (GLP-1R) biased agonist designed to be dosed once daily orally and once monthly ...

No vomiting was seen in this dose group. - Data from three different ... small molecule GLP-1 receptor (GLP-1R) biased agonist designed to be dosed once daily orally and once monthly ...

Mirror Agonists? First-in-human Phase 1 studies of AL002 (left ... Kaufmann said. Kaufmann also showed a dose-response curve that plotted the sTREM2 concentration of individual participants. In the ...

Using these dose-response curves, we also estimated the cardiovascular and general health equivalence of MIPA and LIPA against each minute of VIPA. The UK Biobank is a prospective cohort study of ...

A new Brevia (peer-reviewed research report) published in Brain Medicine reveals that a single dose of the drug Osanetant ... offering a rapid-response pharmacological shield against trauma ...

Introduction: The biphasic dose-response behavior, also known as hormesis, is a characteristic feature of numerous natural products. It is defined by beneficial effects at low concentrations and ...

In addition, we determine the structures of C3aR in complex with the synthetic small-molecule agonist JR14a in two distinct conformational states: a G protein-free intermediate, and a fully active G i ...

A ligand dose–response curve with the photoactivatable agonist 11-cis-retinal showed a half-maximal signal at 120 nM. Our findings may be useful to develop novel assay formats for GPCRs based on ...

Stylized curves that illustrate the linear, threshold, and hormetic dose-response models for carcinogens. The central pillar upon which toxicological assessments are built is the dose-response ...