Relevant biomarkers include cytokines and targets such as IL-4, IgE, IL-5, IL-13, IL-33, and TSLP (Figure 2). A number of ...

Enzymes, such as γ-secretase, are able to cleave and release the extracellular domain of BCMA into the bloodstream as soluble ...

Berkeley scientists have developed a smartphone-based biosensor that mimics coffee-ring physics to detect disease proteins ...

VISTA, an AI-controlled data loop system, guides large-scale antibody design from scratch for applications in cancer therapy.

Traditional therapeutic antibody development has been constrained by long screening processes, and de novo antibody design requires a deep understanding of how the entire protein sequence affects ...

Antibody–siRNA conjugates (ARCs) are a type of promising drug modalities for cancer therapy. However, initial reports of ARCs present the gene knockdown effect only in limited tissues (e.g., muscles) ...

To develop a covalent modifier for the amyloid-forming protein β-2-microglobulin (magenta), researchers used a nanobody (teal ...

SAN FRANCISCO, June 30, 2025--Chai Discovery, which builds frontier artificial intelligence to predict and reprogram the interactions between biochemical molecules, today announced a breakthrough in ...

Using AI and Multiplexed Gene Fragments, researchers developed a novel design approach to encode thousands of single-domain antibodies without compromising sequence integrity.