Most organisms fit comfortably into standard definitions of “life,” i.e., cells that grow, reproduce independently, and ...

Background The elimination of HBV covalently closed circular DNA (cccDNA) remains a critical hurdle for ... Combination therapy with IFN-α effectively suppressed HBV replication, achieving a 60% ...

Drs Ursula A. Matulonis and Joyce F. Liu discuss targeting DNA damage and repair and replication stress in endometrial cancer.

Extrachromosomal DNAs (ecDNAs) are circular DNA structures located in the nuclei of cells outside chromosomes. They were originally discovered in chromosome spreads of cells obtained from ...

Cryo-electron microscopy reveals hidden mechanics of DNA replication, sheds new light on cancer target Date: March 10, 2025 Source: Memorial Sloan Kettering Cancer Center Summary: Researchers shed ...

MSK researchers shed new light on G-quadruplexes, a type of secondary DNA structure that has attracted attention as a potential therapeutic target in cancer.

Three students from Centreville High School in Clifton discovered a potentially harmful substance – DNA residues, or tiny fragments of genetic material – in Pfizer’s messenger RNA COVID-19 ...

A protein that is involved in determining which enzymes cut or unwind DNA during the replication process has been identified.

A protein that is involved in determining which enzymes cut or unwind DNA during the replication process has been identified in a new study.

Mrc1 is part of a group of proteins called the fork protection complex (FPC), which is part of the replisome, a molecular machine that coordinates the replication of DNA, a process that includes ...

The eukaryotic replisome is assembled around the CMG (CDC45-MCM-GINS) replicative helicase, which encircles the leading-strand DNA template at replication forks. When CMG stalls during DNA replication ...