In this valuable study, the authors provide a simple yet elegant approach to identifying therapeutic targets that synergize to prevent therapeutic resistance in ovarian cancer using cell lines, ...

GTP Hydrolysis: The enzymatic conversion of guanosine triphosphate (GTP) to GDP, driving conformational changes in tubulin and underpinning dynamic instability.

Through this, they identified five different cancer cell groups within a tumor, with distinct gene expression profiles that indicated vast differences in cell behavior.

Darwinian evolution says that complex systems arise through numerous successive, slight modifications that benefit the species' survival over many generations. However, we have shown that bacterial fl ...