In every living cell, there are membranes, and in every membrane there are proteins, each of which acts as a chemical ...

Immune responses rely on the efficient movement of immune cells within the complex and geometrically unpredictable ...

Researchers from The University of Osaka find the key proteins that maintain optimal pH within the Golgi apparatus by ...

Discover what glycan analysis can reveal about protein behavior and how it can be used to boost biologic performance and ...

Our cells carry out hundreds of thousands of important functions every day, all of which are carefully orchestrated at a microscopic scale. However, the precise mechanisms that influence the luminal ...

In addition, the cells showed defects in protein glycosylation, a major enzymatic reaction performed in the Golgi and trans-Golgi network.

CAMSAP2 is dynamically localized at the Golgi during the reorientation process in directional cell migration. (A) Immunofluorescence staining of HT1080 located at the foremost edge of the cell wound ...

Not revised: This Reviewed Preprint includes the authors’ original preprint (without revision), an eLife assessment, public reviews, and a provisional response from the authors. This work by the Meng ...

What if treating autoimmune diseases was as simple as regulating the acidity levels of parts of patients' cells? Genetic screening may have unlocked a path for treating the severe inflammation ...

The Golgi apparatus is a central hub in the intracellular secretory pathway. By positioning in the specific intracellular region and transporting materials to spatially restricted compartments, the ...

Researchers investigating ways to reduce exhaustion in cancer-fighting T-cells found that the Golgi apparatus can be used as a simple marker -- more Golgi means a more robust cell.