The natural protein universe is vast, and yet, going beyond and designing new proteins not observed in nature can yield new ...

Aging-related diseases, including cancer, cardiovascular disorders and type 2 diabetes, are associated with defects in ...

In a study published in Nature Metabolism, researchers at the University of Michigan found that mitochondria also accumulate misfolded proteins, which kills β-cells.

The strategies biopharmaceutical manufacturers currently use to limit protein misfolding are complex, time-consuming, and generate low yields with only limited scalability. Covalent organic ...

Discover how AI tools like AlphaFold and RF Diffusion are revolutionizing protein folding design, medicine, and sustainability for a better ...

By looking for missteps in the intricate process of folding proteins, a project at Purdue University is paving the way for a new generation of therapeutics that strike at the root of these diseases.

Understanding protein folding is important not only for biology, but also for medicine, where researchers are exploring ways to correct misfolded proteins to treat diseases.

Understanding how exactly protein folding occurs remains a key challenge for scientists, and this co-translational folding provides the way in which cells ensure the safe and efficient production ...

Scientists at UCL have discovered a novel role played by ribosomes during the folding of new proteins in cells, described in their paper in Nature.

Scientists at UCL have discovered a novel role played by ribosomes during the folding of new proteins in cells, described in their paper in Nature.