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Dr. Deepak Nair, a leading neurologist with OSF Healthcare’s Illinois Neurological Institute, said that exercise, sleep, and ...
Omega-3 fatty acids are a type of essential fats linked to many health benefits, such as heart health, reduced inflammation, ...
ALZHEIMER’S disease (AD), a neurodegenerative condition marked by cognitive decline and progressive memory loss, has long been associated with chronic inflammation and immune dysregulation. Regulatory ...
JNJ which has outperformed the S&P 500 and other large-cap healthcare peers in H1-2025, now faces a crucial test with Q2 results due to be announced on ...
It functions by both blocking the PD-1/PD-L1 pathway and activating the IL-2 pathway. The IL-2 arm of IBI363 is designed to maintain its affinity for IL-2Rα while reducing binding to IL-2Rβ and IL-2Rγ ...
Background It is unclear if type-2 inflammation is associated with accelerated lung function decline in individuals with asthma and chronic obstructive pulmonary disease (COPD). We tested the ...
Cilia loss and impaired motile ciliary functions are common in chronic rhinosinusitis with nasal polyps (CRSwNP). IL-17A and IL-22, key cytokines in type 3 inflammation, affect epithelial cell ...
CD8 + T cells have critical roles in tumor control, but a range of factors in their microenvironment such as low pH can suppress their function. Here, we demonstrate that acidity restricts T-cell ...
Here, we demonstrate that acidity restricts T-cell expansion mainly through impairing IL-2 responsiveness, lowers cytokine secretion upon re-activation, and reduces the cytolytic capacity of CD8 + T ...
They also found a link between abnormal IL-9 levels and uncontrolled secretion by T helper 9 (Th-9) cells, which the authors said suggests “that CLL and Th-9 cells potentially cooperate to shape ...
These findings strongly suggest a major role for both IL-6 trans-signaling and IL-1β signaling in the pathological increase in permeability of the human lung microvasculature and reveal combinatorial ...