Interleukin-2 (IL-2) is a cytokine that is critical to the regulation of T-cell responses. IL-2 also has a huge range of immunostimulatory and immunomodulatory functions.

Interleukin-2 (IL-2) inhibitors are immunosuppressive agents that block the activity of IL-2, a cytokine involved in the activation and proliferation ...

These in vivo differences suggest that, although IL-15 and IL-2 exert some common in vivo functions, they also have key distinct functions, as illustrated by the following observations.

Please use one of the following formats to cite this article in your essay, paper or report: APA. Lightfoot, Colin. (2021, October 07). Critical function of IL-7 in diagnosis, prognosis, and ...

Intrinsic IL-2 production by effector CD8 T cells affects IL-2 signaling and promotes fate decisions, stemness, and protection. Science Immunology, 2022; 7 (68) DOI: 10.1126/sciimmunol.abl6322; ...

XmAb564 is engineered with reduced binding affinity for IL-2's beta receptor (IL-2Rβ, CD122) and increased binding affinity for its alpha receptor (IL-2Rα, CD25).