Interleukin-2 (IL-2) inhibitors are immunosuppressive agents that block the activity of IL-2, a cytokine involved in the activation and proliferation ...

Researchers from UCLA published a Perspective in Science Bulletin proposing bioengineered platforms that mimic immunological synapses to improve CAR-T cell manufacturing. Their strategies offer ...

Relevant biomarkers include cytokines and targets such as IL-4, IgE, IL-5, IL-13, IL-33, and TSLP (Figure 2). A number of targeted drugs are currently available, including lebrikizumab, dupilumab, and ...

Autoimmune hepatitis (AIH) is a chronic, progressive inflammatory liver disease driven by autoimmune mechanisms, characterized by elevated serum ...

Chimeric antigen receptor T cell therapy has reshaped expectations for treating hematological malignancies and is now reaching toward autoimmune ...

This study provides valuable findings regarding potential correlates of protection against the African swine fever virus. The evidence supporting the claims is solid, although analysis using a higher ...

Explore the latest advancements in immunotherapies for T-cell lymphoma, addressing unique challenges and promising new ...

Since the February update, an additional 5 patients have been dosed, resulting in 2 Complete Responses (CR) and 3 Partial ...

Cytokine networks demonstrate dual functionality. Cytokines are key regulators of immune homeostasis, but paradoxically, cytokines also function as pathogenic drivers in diseases such as systemic ...

Air pollution is a global health concern, with over 90% of the world's population breathing air that exceeds World Health ...