Current approaches in bioengineering are synthesized and methods for their implementation are suggested for the induction and modulation of trained immunity in the treatment of human diseases.

Air pollution is a global health concern, with over 90% of the world's population breathing air that exceeds World Health ...

This study provides valuable findings regarding potential correlates of protection against the African swine fever virus. The evidence supporting the claims is solid, although analysis using a higher ...

Since the February update, an additional 5 patients have been dosed, resulting in 2 Complete Responses (CR) and 3 Partial ...

A team at the Peter Mac is planning for first-in-human trials in five years, hoping this new therapy will eschew the ...

Interleukin-2 (IL-2) inhibitors are immunosuppressive agents that block the activity of IL-2, a cytokine involved in the activation and proliferation ...

Calidi Biotherapeutics Inc. has spent over 10 years developing a groundbreaking platform for the systemic delivery of genetic medicines that can precisely target tumors. One of the company's core ...

Each year, approximately 20 million people are diagnosed with cancer, and nearly 10 million lives are lost to the disease worldwide, a ...

Researchers from UCLA published a Perspective in Science Bulletin proposing bioengineered platforms that mimic immunological synapses to improve CAR-T cell manufacturing. Their strategies offer ...

In T cell receptor (TCR) preactivated cells, before IL-2 stimulation, substantial H3K27Ac was evident in the superenhancer region, indicating that the chromatin was already “active” and these ...