Notably, IM and SC dosing every three months reflected robust efficacy for both IC and non-IC individuals and such routes could simplify and scale administration, improving convenience.

Figure 1 shows the comparison of the three routes of injection of Mercuhydrin: intramuscular, intravenous and subcutaneous. Each of the points represents the same 22 patients.

Gilead picked the intramuscular route because of the amount of drug needed to be delivered and a better pharmacology profile compared with a subcutaneous injection, according to Baeten.

The intramuscular route is used for all patients with overt lead encephalopathy and this route is preferred by some for young pediatric patients.

Table 2 compares the clinical response to intramuscular injection of reserpine in these 10 patients with onset of effect, time of maximal effect, dose and appearance of side effects.

The 100% sufficiency rate observed in the IM group by 12 weeks illuminated the potential of this route for individuals who struggle with oral supplementation or require rapid correction of vitamin D ...

In Crossject’s study, ZEPIZURE® was equivalent to the IM injection from a syringe equipped with a 30mm needle (Dormicum®), and results also suggested a 2-fold lower variability as compared to that ...

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