Botensilimab/balstilimab (BOT/BAL) synergistically activate and sustain immune attack, offering a promising new strategy for ...

Researchers sought to determine whether adding elotuzumab to PVd would be safe and effective in treating patients with relapsed or refractory MM.

St. Louis, Oct.20, 2008 — Researchers have shown that self-induced breaks in the DNA of immune cells known as lymphocytes activate genes that cause the cells to travel from where they're made to ...

From bench to bedside: targeting lymphocyte activation gene 3 as a therapeutic strategy for autoimmune diseases. Inflamm Res. 2023 Jun;72(6):1215-1235. doi: 10.1007/s00011-023-01742-y.

This may suggest the presence of a link between glucose metabolism and lymphocytes activation. Antidiabetic medications could promote the inhibition of Warburg effect in tumor cells, and, consequently ...

MALAT1-anti-correlating genetic signatures showed enrichment of T lymphocyte activation, oxidative phosphorylation, cell division, and cytokine response genes. Related Stories.

Nivolumab and relatlimab had a manageable safety profile that was consistent across study cohorts, with no treatment-related deaths. Objective response rate by blinded independent central review ...

Initial pharmacological data from placebo-controlled, double-blind Phase I study shows significant T cell suppression and a favourable safety profile at dosing level of 0.9 mg/kgThe substantial ...

Influenza hemagglutinin subunit vaccines are more effective and offer better cross protection against various influenza virus ...

Instead, the study analysis uncovered that complete cytokinopathy and activation of cytotoxic lymphocytes with unique transcriptional signatures characterized mRNA-LNP vaccine-induced myopericarditis.