In a paper published in Science Bulletin, the research team led by Professor Wen Zhang from the Department of Rheumatology and Immunology at Peking Union Medical College Hospital (PUMCH) has made ...

ImmunityBio, Inc. (NASDAQ: IBRX) today announced that the UK Medicines and Healthcare products Regulatory Agency (MHRA) has granted marketing authorization for ANKTIVA® (nogapendekin alfa ...

Coblockade of lymphocyte activation gene-3 (LAG-3) and PD-1 receptors could provide significant clinical benefit for patients with advanced melanoma. Fianlimab and cemiplimab are high-affinity, human, ...

Intriguingly, elongation rates can be increased up to 30% by activation in vivo or fever temperature in vitro. Resting and activated lymphocytes possess abundant monosome populations, most of which ...

The interconnection between cellular metabolism and lymphocyte activation as a prognostic factor in patients affected by metastatic pancreatic ductal adenocarcinoma treated with gemcitabine and ...

Conclusions: Our data clearly demonstrate antigen-specific activation of T lymphocytes infiltrating ischemic brain lesions in stroke. The high expression of inhibitory PD-1 and low expression of CD25 ...

Activation of T lymphocytes constitutes a central event in adaptive immune responses. Antigen recognition by T cells through the T cell receptor (TCR) triggers a cascade of intracellular signals ...

T lymphocyte activation is triggered by the recognition via the T-cell receptor (TCR) expressed at the surface of T lymphocytes, of antigenic peptides, derived from pathogens or tumors and associated ...