M13 phage can be administered in PBS in mice to evoke a strong primary IgG response that is dependent on MyD88 signaling (Ref.1). Even a single immunization with 1011 pfu of phage induced a ...

M13 phage, a filamentous phage, showed intermediate susceptibility, with higher inactivation rates in BM, which could be attributed to its elongated morphology, increasing surface interaction with ...

This study reveals the potential of engineered phage-IL-12 therapy in melanoma, enhancing immune response and tumor destruction in aggressive cancer models.

Filamentous bacteriophage (fd or M13) is commonly used in phage display experiments. In addition, the phage has recently been used in the bio-nanotechnology and biomaterial fields. To explore the ...

M13 bacteriophage (phage) was engineered for the use as a versatile template for preparing various nanostructured materials via genetic engineering coupled to enzymatic chemical conversions. First, we ...

The Phage Whisperer Biswajit Biswas drew a syringe full of phage and injected it into his laboratory mice, one after another. The mice weren't sick, so he wasn't using phages as medicine.

Technologies for generating superphages and optimizing phage cocktails are poised to overcome antibiotic resistance and resolve microbiome dysbiosis.

Phage therapy offers hope for fighting bacteria that have become resistant to antibiotics. The FDA needs to loosen restrictions on its use.

This valuable work describes a new protein factor that is required for filamentous phage assembly. Convincing evidence is provided for the binding of PSB15 to the packaging signal of the ...

At least five phage-specific proteins, including the two coat proteins, are present in appreciable quantities in M13-infected cells. The principal phage protein synthesized is the product of gene 5, ...