FDA approves the first treatment for KRAS-mutated recurrent low-grade serous ovarian cancer (LGSOC), offering new hope for ...

In the published article, there was an error in the Funding statement. Due to their own negligence, the number of some funded projects is repeated. Talent Innovation ...

In a recent paper, published in Nature, researchers from the University of Michigan have discovered that simultaneously targeting PIKfyve and KRAS-MAPK can eliminate tumors in preclinical human and ...

Our findings demonstrate that DAPA can inhibit the MAPK signaling pathway, as confirmed by network pharmacology analysis and molecular docking experiments. Results: DAPA ameliorates ISC aging, ...

Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo n. 2, Prague 6 16610, Czech Republic Department of Physical and Macromolecular Chemistry, Faculty of ...

These pathways include nuclear factor- B, p38 mitogen-activated protein kinase, NH 2-terminal Jun kinases/stress-activated protein kinases, hexosamines, and others. In addition, there is evidence ...

2Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina. 4Structural Genomics Consortium and Division of Chemical Biology and Medicinal ...

Terms of Service and Privacy Policy. After two long years, the highly anticipated second season of HBO’s The Last of Us is almost here. In the new season, five ...

Summary: Scientists have discovered a new protein pathway involved in neurodegeneration by studying “mini-brain” organoids made from patients with frontotemporal lobar degeneration (FTLD). They found ...