From Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville Campus, Victoria, Australia (R.H.R.) Division of Endocrinology and Metabolism (E.D.A.), ...

Background Injured or reactive biliary epithelial cells participate in most chronic liver injuries in a process referred to as ductular reaction, which involves multicellular interactions with marked ...

Key Laboratory of Industrial Fermentation Microbiology of the Ministry of Education; Tianjin Key Laboratory of Industrial Microbiology, College of Biotechnology, National Engineering Laboratory for ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Global hepatic DNA methylation change has been ...

Department of Integrative Oncology, Fudan University Shanghai Cancer Center, Shanghai 200032, P. R. China Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, P. R.

As a result, our study demonstrated that NADPH sources for lipogenesis include the OxPP pathway, POM cycle, and isocitrate-2-oxoglutarate shuttle in Y. lipolytica. Moreover, the knockout of ...

We identify the ROS-generating NADPH oxidase-4 (Nox4) as an essential regulator of exercise performance in mice. Myocardial Nox4 levels increase during acute exercise and trigger activation of the ...

Activation of the phagocyte nicotinamide adenine dinucleotide phosphate (NADPH) oxidase constitutes an emergency response to infectious threat and results in the generation of antimicrobial reactive ...