Glycerol is used as an energy substrate via glycolysis or participates in gluconeogenesis and lipogenesis. Glycerol is oxidised and exhaled as carbon dioxide, with minimal excretion via urine or ...

Metabolic reprogramming is a hallmark of hepatocellular carcinoma (HCC), with enhanced de novo lipogenesis playing a critical role in tumor progression. ATP citrate lyase (ACLY), linking carbohydrate ...