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BRILINTA is indicated to reduce the risk of stroke in patients with acute ischemic stroke (NIH Stroke Scale ≤5) or high-risk transient ischemic attack (TIA). DOSING .
Researchers observed that the median NIH Stroke Scale score was higher in patients with COVID-19 (OR = 1.69; 95% CI, 1.08-2.65) compared with patients without COVID-19.
Unfortunately, this scale is only recorded about 40 percent of the time; we separately derived a risk score in patients whose NIH Stroke Scale score was recorded.
Stroke specialists conducted emergency clinical assessments with all patients, including the NIH Stroke Scale which is used to measure stroke severity. MRI was done prior to CT in 304 patients.
The researchers randomly assigned 760 patients (median age, 64 years; 31% women) with minor nondisabling acute ischemic stroke — defined as NIH Stroke Scale score of 5 or less, plus 1 point or ...
All referred patients included in the development dataset were assessed by either a senior member of the stroke team or a research neurologist certified to use the NIH STROKE SCALE (NIHSS). All ...
Secondary outcomes were in-hospital symptomatic ICHs (ECASS-2 criteria, i.e., NIH Stroke Scale score increase of ≥ 4 points) and any in-hospital ICHs. “A total of 3,953 patients were treated ...
The strokes were rated as severe (median 22 on the National Institutes of Health (NIH) Stroke Scale, which assesses a patient's ability to perform normal functions such as speaking and moving) and ...