Biotech firms are engineering smarter, safer gene delivery systems to enhance the safety and efficacy of genetic medicines.

CD4 T helper cells are a type of white blood cell called a lymphocyte that serves an important role in your immune system. These cells help defend the body against infection by directing other "killer ...

The partnership aims to commercialise cell therapies for solid tumour treatments. Credit: Freedomz / Shutterstock. South Korea-based DAAN Biotherapeutics has entered a licensing agreement with GC Cell ...

OT-C001 is an allogeneic cell therapy of highly activated and expanded NK cells from UCB, manufactured using a patented expansion and activation process. It targets tumor cells through direct and ...

A number of signalling pathways have been identified as crucial in controlling NK cell metabolic and functional responses. Interestingly, the levels of nutrients and metabolites within the immune ...

FAYETTEVILLE, GA, UNITED STATES, April 16, 2025 /EINPresswire.com/ -- This study uncovers dynamic immune adaptations during ...

Introduction: The CD4/CD8 ratio has emerged as a useful indicator of immune dysfunction and comorbid conditions in people living with HIV (PLWH). However, its optimal cut-off value is unclear. We ...

This study utilized a single-cell analysis of public database to identify four cell types: CD4 + T cells, Mac, naïve T cells, and NK cells. We performed an enrichment analysis of these cell ...

CAR T-cell therapies have drastically changed treatment paradigms in R/R haematological malignancies since the first approval in 2017. Credit: Meletios Verras via Shutterstock. Chimeric antigen ...

This study presents a useful reassessment of the potential role of dendritic cell-derived IL-27 p28 cytokine in the functional maturation of CD4+CD8- thymocytes, and CD4+ recent thymic emigrants. The ...

A CD30×CD16A bispecific antibody is helping off-the-shelf natural killer cells home in on cancer targets, showing strong responses in patients with relapsed or refractory lymphoma. Early clinical ...