Endothelial nitric oxide synthase uncoupling and perivascular adipose oxidative stress and inflammation contribute to vascular dysfunction in a rodent model of metabolic syndrome. Hypertension ...

Endothelial dysfunction occurs commonly in diabetes and insulin resistance. This Review describes mechanisms that promote development of atherosclerosis in these conditions through changes in ...

The prevalence of obesity has been increasing in the US. In 2017–2018, the prevalence was 42.4%, an increase from 30.5% in 1999-2000. 1 Obesity is linked to numerous health problems, many of ...

By replicating conditions like tissue stiffening and scarring - common in aging, chronic diseases and cancer - the researchers discovered that perivascular cells drive blood vessel leakage and ...

David Manka, PhD, a researcher in the division of cardiovascular diseases, and his team found that this fat -- known as perivascular adipose tissue -- could possibly lead to the formation of fatty ...

Otherwise known as perivascular cells, the specialised cells sense changes in nearby tissues and send signals that disrupt blood vessel function, therefore making disease progression worse. A new ...

Researchers at Oregon Health & Science University have uncovered how specialized cells surrounding small blood vessels, known as perivascular cells, contribute to blood vessel dysfunction in chronic ...

This study demonstrates that global or adipose tissue-specific knockout of CIDEC/FSP27 significantly reduces AAA incidence after HFD treatment and Ang Ⅱ infusion, providing novel insights into ...

Previous research showed that obesity heightens the risk of severe COVID-19 regardless of age, sex, ethnicity and comorbidities such as diabetes, high blood pressure, and heart or lung disease ...

Previous research has also established that inherent permeability of mesenteric and peripheral collecting lymphatic vessels enables distribution of lymph components to surrounding adipose tissue. Thus ...

Based on perivascular adipose-tissue samples and coronary CT images from more than 400 patients, they developed a "fat-attenuation index" (FAI) that correlates with coronary artery inflammation ...