By tracking plasmids that were selectively depleted, we identified over 100 candidate phage trigger- E. coli pairs. Two phage trigger proteins were investigated in detail, revealing a novel antiphage ...

The primary criticism of phage therapy is generally that a paucity of modern, double-blinded, Phase III (efficacy) clinical trials in humans have been undertaken and, therefore, a substantial ...

As difficult-to-treat infections continue to rise, phage therapies are becoming important complements to existing treatments.

As antibiotic resistance reaches critical levels worldwide, the 8th World Congress on Targeting Phage Therapy (June 10–11, 2025) returns to Berlin, bringing together over 75 international ...

Nearly Forgotten ‘Phage Therapy’ Fights Antibiotic Resistance In a new book, a science journalist recounts the story of a lifesaving treatment for infection that scientists broadly dismissed ...

Technologies for generating superphages and optimizing phage cocktails are poised to overcome antibiotic resistance and resolve microbiome dysbiosis.

Additionally, efforts to engineer phage display systems with enhanced stability, specificity, and functionality are ongoing, further enhancing the utility of this technique in biotechnology and ...

In turn, a phage will try to coevolve with the bacteria to maintain its infectivity. Sometimes a phage can change to better infect its target bacteria, but sometimes the bacteria can outsmart it.