In the treatment of bacterial infectious diseases, overuse of antibiotics may lead to not only bacterial resistance to antibiotics but also dysbiosis of beneficial bacteria which are essential for ...

By tracking plasmids that were selectively depleted, we identified over 100 candidate phage trigger- E. coli pairs. Two phage trigger proteins were investigated in detail, revealing a novel antiphage ...

Learn how GraphRAG transforms unstructured text into structured data, revolutionizing AI retrieval with deeper insights and connections.

About BiomX Inc. BiomX, Inc. operates as a clinical-stage microbiome company, which engages in the development of both natural and engineered phage cocktails designed to target an ...

Finally, a host specificity-aware graph autoencoder is proposed to learn high-quality representations of phages and bacteria for predicting phage-host interactions.

In methicillin-resistant Staphylococcus aureus, evolution of bacteriophage resistance causes trade-offs that re-sensitize the bacteriato β-lactam antibiotics.

Additionally, efforts to engineer phage display systems with enhanced stability, specificity, and functionality are ongoing, further enhancing the utility of this technique in biotechnology and ...

With phage therapy, researchers sharpen another arrow in the quiver against antibiotic resistance.