The natural protein universe is vast, and yet, going beyond and designing new proteins not observed in nature can yield new ...

Bacterial cell division, a process wherein a single cell divides to form two identical daughter cells, represents one of the ...

This protocol refines co-immunoprecipitation (co-IP) for lipid droplet (LD)-specific protein interactions by isolating ...

The thinking was that proteins needed to be big in order to carry out complex chemistry. But in fact a lot of the new proteins turning up were smaller than 100 amino acids long.

Synopsis hu.MAP3.0 integrates mass spectrometry experiments to identify human protein complexes. Using this resource, this study characterizes covariation of complexes, identifies mutually exclusive ...

New protein-protein docking algorithm combining deep learning (AlphaFold2) and physics (Rosetta and enhanced sampling) achieves high success rates.

This study resolved the cryo-EM structures of the Nipah virus polymerase complex, unveiling the binding mode between the RdRp/PRNTase domains of the L protein and the P tetramer.

A structural proteomics approach for identifying candidate interactors of any protein within a complex lysate is presented. It is applied to identify conformation-specific interactors of Rab GTPases ...

Successful research in targeted protein degradation depends not only on measurements at high sensitivity, speed and precision but also on having the flexibility to accommodate emerging assays.

Proteins interact with other proteins and bio-molecules to form a complex and execute key biological functions in a living organism, and respond to several environmental signals. Designing efficient ...

Proteomics - Immunoprecipitation: Understand the significance of proteins in biological research and the role of immunoprecipitation: After listening to the podcast, learners will be able to explain ...