A predictive biophysical model that integrates protein-DNA structures and sequences to accurately determine genomic binding sites and affinities of DNA-binding proteins.

Without the receptor, ADGRG1, the microglia barely nibbled on the toxic protein. Using a mouse model of Alzheimer’s disease, the researchers observed how the loss of ADGRG1 led to the rapid buildup of ...

AI in Cancer Drug Discovery could prove paradigm shifting, but what challenges does it present? And how can they be avoided?

The natural protein universe is vast, and yet, going beyond and designing new proteins not observed in nature can yield new ...

Researchers identified SDR42E1 as a key regulator of vitamin D absorption and sterol metabolism in colorectal cancer cells.

These Immune Cells Eat Molecular Trash to Keep Alzheimer's at Bay UCSF scientists have discovered how microglia engulf and break down amyloid beta, a protein that builds up in Alzheimer’s, with ...

A research team developed a novel method using bidirectional reflectance factor (BRF) spectra combined with the PROSPECT-PRO ...

What if your doctor could, when you turn 65, order a test that predicts whether you are going to develop Alzheimer’s dementia in your 70s or 80s? And what if – in case the test comes back ...

AI startups (>27K), tools (>70K), and GitHub repos highlight proliferation. Patents in computing/AI are booming, signaling a ...

Every living cell must interpret its genetic code—a sequence of chemical letters that governs countless cellular functions. A new study by researchers from the Center for Theoretical Biological ...

A new study, published in Nature Communications, focuses on a protein called PopA, found in the bacterial predator Bdellovibrio bacteriovorus. The protein forms a unique fivefold structure, unlike the ...

New foundational AI models are accelerating advancements in biomedical research, according to a speaker at Cleveland Clinic’s ...