Without the receptor, ADGRG1, the microglia barely nibbled on the toxic protein. Using a mouse model of Alzheimer’s disease, the researchers observed how the loss of ADGRG1 led to the rapid buildup of ...

Large-scale redesigns, including changes to core domains, may retain stability—challenging assumptions that such regions are off-limits.

Researchers identified SDR42E1 as a key regulator of vitamin D absorption and sterol metabolism in colorectal cancer cells.

What if mRNA vaccines could be made more powerful and less irritating? Scientists at the University of Pennsylvania have ...

Contrary to long-standing assumptions, human egg cells stay pristine for decades not by ramping up waste disposal, but by ...

A predictive biophysical model that integrates protein-DNA structures and sequences to accurately determine genomic binding sites and affinities of DNA-binding proteins.

Every living cell must interpret its genetic code—a sequence of chemical letters that governs countless cellular functions. A new study by researchers from the Center for Theoretical Biological ...

This important study fills an gap in our knowledge of the evolution of GPCRs in holozoans, as well as the phylogeny of associated signaling pathway components such as G proteins, GRKs, and RIC8 ...

A new study, published in Nature Communications, focuses on a protein called PopA, found in the bacterial predator Bdellovibrio bacteriovorus. The protein forms a unique fivefold structure, unlike the ...

Protein coffee or 'proffee' is an easy way to get more protein in the morning, which can help you lose weight, build muscle and more. How to make it taste good.

Protein coffee or 'proffee' is an easy way to get more protein in the morning, which can help you lose weight, build muscle and more. How to make it taste good.

Natural structural-protein-based elastomeric materials have garnered significant attention as potential alternatives to synthetic polymers, due to their remarkable biodegradability, biocompatibility, ...