Apart from carrying the information to encode proteins in, RNA molecules can adopt intricate 2D and 3D structures.

Proteins are life's molecular workhorses, doing everything from turning sunlight into food to fighting viruses. They are ...

Greedy accumulation-directed evolution generated multi-site combinatorial mutants of T7 RNA polymerase (T7 RNAP), breaking ...

What made ribose the sugar of choice for life's code? Scientists at Scripps Research may have cracked a major part of this ...

The cold sore-causing Herpes Simplex Virus (HSV-1) hijacks human cells and reconfigures its DNA within just an hour after infection, according to a new study that may help tackle the pathogen.

With the long-term goal of creating living cells from non-living components, scientists in the field of synthetic biology work with RNA origami. This tool uses the multifunctionality of the natural ...

MDL-001 targets a part of the RNA-dependent RNA polymerase enzyme that the viruses use to replicate their genetic material.

Synthetic biologists working with DNA and RNA often run into an unhelpful nemesis called T7 RNA polymerase enzyme, which Lucks compares to the radio battery for its role in pumping out output signals.

A useful bug in the system Synthetic biologists working with DNA and RNA often run into an unhelpful nemesis called T7 RNA polymerase enzyme, which Lucks compares to the radio battery for its role in ...

The RNA polymerase complex of the Nipah virus is responsible for both replication and transcription of the viral RNA genome. This study elucidates the structure of the RNA polymerase in complex with ...

The landmark discovery by Founding Department Chair Joseph Kates, PhD, that viruses could package enzymes required for their replication, with the first demonstration of the vaccinia virus ...