An RNA polymerase II molecule is about 15 nanometers across, or roughly 5,000 times smaller than the width of a human hair. Technique This image was created by reconstructing X-ray diffraction ...

RNA polymerase II, or Pol II, doesn’t start working on its own. ... Overall, the resulting structures are strikingly similar, though each structure contains a slightly distinct view.

Finally, using cryo-electron microscopy, they captured the 3D structure of the RNA polymerase in its active, RNA-bound state at molecular resolution. Implications for Future Treatments.

Aclarubicin stimulates RNA polymerase II elongation at closely spaced divergent promoters. Sci Adv. 2023 Jun 16;9(24):eadg3257. doi: 10.1126/sciadv.adg3257. Facebook LinkedIn Twitter Email Bluesky ...