The aromatic amino acids (AAAs) histidine, phenylalanine, tryptophan, and tyrosine have a side chain with an aromatic ring and are precursors of dopamine, epinephrine, norepinephrine, serotonin, and ...

By identifying the critical role the urea cycle plays in its development, his findings could pave the way for new medications to treat this currently incurable disease.

New research explores the urea cycle's strong connection to fatty liver disease Date: August 13, 2024 Source: Indiana University School of Medicine Summary: A physician scientist is making strides ...

Article Title Hierarchical tricarboxylic acid cycle regulation by hepatocyte arginase 2 links the urea cycle to oxidative metabolism ...

Concurrently, the biocatalysis cycle using a PLP enzyme modifies the amino acid substrate via a series of activation steps unique to PLP biochemistry.

Amino acids are produced 2.4 million ton per year all over the world. The Ajinomoto Group produces them mainly from sugars or starches through fermentation process and a large amount of organic ...

Unfortunately, mechanisms regulating L-arginine synthesis, plasma levels and intracellular availability remain elusive and attempts to enhance L-arginine availability for eNOS activity by oral intake ...

Here, we used time-lapse microscopy and single-cell tracking of cyclin-dependent kinase 2 (CDK2) activity to assess the response of individual cells to withdrawal of single amino acids and found ...

Article citations More>> M. C. Stumpe and H. Grubmüller, “Interaction of Urea with Amino Acids: Implications for Urea-Induced Protein Denaturation,” Journal of the American Chemical Society, Vol. 129, ...

Urea cycle metabolism is disturbed in Fibrolamellar carcinoma. [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2023; Part 1 (Regular and Invited Abstracts); ...

However, the association between amino acids related to urea cycle and CKD in T2DM was largely unknown. We conducted a cross-sectional survey in a Chinese population with T2DM to investigate any ...