Abstract Atrial fibrillation (AF) and coronary artery disease are frequently associated and, when so, lead to a grim prognosis. Recent studies suggest the presence of interconnected pathophysiological ...

Hypertrophic cardiomyopathy (HCM) is a heterogeneous disorder with varying risks of clinical outcomes, including sudden cardiac death (SCD). We aimed to identify distinct phenotypes among patients ...

Increased left atrial pressure (LAP) contributes to dyspnea and heart failure with preserved ejection fraction in patients with atrial fibrillation (AF). The purpose of this study was to investigate ...

Here, we review recent mechanistic and clinical evidence suggesting an additional preventive strategy for patients at risk for AF and patients after thoracic and cardiac surgery, namely, treatment ...

The pro- and antiarrhythmic effects of omega-3 polyunsaturated fatty acids (n-3 PUFAs) have been extensively studied in preclinical and human trials. Despite early evidence of an antiarrhythmic role ...

Inhibition of renin expression in cells that constitutively synthesize and release renin is regulated by an epigenetic switch from an active to poised state associated with decreased cell-cell ...

Although overt atherosclerotic disease (especially when clinically symptomatic) is comparatively easy to see, its future development in an asymptomatic population is hard to foresee. Indeed, at the ...

Overweight or obesity results in a wide range of elevated risk factors and many fatal and nonfatal conditions. 4 Paradoxically, although we have witnessed decades in which heart disease and stroke ...

From the Department of Medicine, University of California San Diego, La Jolla. A crucially important point needs to be noted here: For whatever reasons, the Japanese have their lower cholesterol ...

BackgroundHIV is associated with elevated risk of heart failure (HF). Despite poor agreement between automated, administrative code–based HF definitions and physician‐adjudicated HF, no studies hav ...

Cardiovascular health can be improved quickly through sound public health measures that have an impact at a population level. 3 Smoke-free workplaces and public places, comprehensive advertising bans, ...

Background—With wide availability of low-cost generics, primary prevention with statins has become less expensive. We projected the cost-effectiveness of expanded statin prescribing strategies using ...