RET/PTC Translocations and Clinico-Pathological Features in …
RET/PTC rearrangements more frequently found in PTC are RET/PTC1, given by the fusion with the CCDC6 (formerly H4) gene and RET/PTC3, given by the fusion with the NCOA4 (formerly …
RET gene rearrangements (RET/PTC1 and RET/PTC3) in papillary …
Jul 13, 2005 · Fresh and paraffin embedded tumor tissues from 215 Japanese patients were examined for RET rearrangements (RET /PTC1 and RET /PTC3) by means of reverse …
RET gene rearrangements (RET/PTC1 and RET/PTC3) in papillary …
Sep 1, 2005 · Methods: Fresh and paraffin embedded tumor tissues from 215 Japanese patients were examined for RET rearrangements (RET/PTC1 and RET/PTC3) by means of reverse …
The importance of the RET gene in thyroid cancer and ... - Nature
Feb 18, 2021 · The most frequent RET fusions in PTC are coiled-coil domain containing 6 (CCDC6)–RET (also named RET–PTC1) and nuclear receptor co-activator 4 (NCOA4)–RET …
RET/PTC1-Driven Neoplastic Transformation and Proinvasive …
We used human NTs and thyrocytes infected with retroviral vector expressing RET/PTC1 (RPTC), or the RET/PTC1-Y451F mutant (RPTC-YF), as a model for PTC to investigate the cross talk …
Use of BRAF and RET/PTC molecular tumor markers in thyroid …
Two genes in particular are associated with thyroid cancer: BRAF and RET/PTC. Two studies were recently done to report the frequency of the BRAF and RET/PTC mutations in patients …
RET Gene Fusions in Malignancies of the Thyroid and Other Tissues
Gene fusion was the first mechanism identified for the oncogenic activation of the receptor tyrosine kinase RET (REarranged during Transfection), initially discovered in papillary thyroid …
Detection of RET rearrangements in papillary thyroid
Jun 1, 2019 · BRAF wild type PTC tissue of 56 patients was analyzed using two established methods: hybrid-specific RT-PCR for the predominant rearrangement RET/PTC1 and …
The RET oncogene in papillary thyroid carcinoma
Mar 2, 2015 · The RET/PTC family of oncogenes, in particular RET/PTC1 and RET/PTC3, plays a key role in the development of some PTCs, especially pediatric PTCs and those associated …
Low prevalence of RET rearrangements (RET/PTC1, RET/PTC2, RET …
The prevalence of RET/PTC1, RET/PTC2, and RET/PTC3 has been found to vary between 0% and 20% in most series of sporadic (nonradiation-induced) PTCs analyzed by type-specific …